Cafe au lait macule - 咖啡牛奶斑https://en.wikipedia.org/wiki/Café_au_lait_spot
咖啡牛奶斑 (Cafe au lait macule) 是扁平、色素沉着过多的胎记。

健康人身上会出现咖啡斑,但可能与 1 型神经纤维瘤病等综合征有关。咖啡斑的数量对于神经纤维瘤病的诊断具有临床意义。青春期前儿童直径至少 5 毫米、青春期后个体直径至少 15 毫米的 6 个或更多斑点是神经纤维瘤病的主要诊断标准之一。

咖啡斑通常在出生时就存在,并且是永久性的,并且可能会随着时间的推移而变大或数量增加。即使在激光手术后,斑点通常也无法完全去除,或者在治疗后可能会复发。

治疗
复发率通常很高,并且需要很长时间的激光治疗。
#QS1064 / QS532 laser
☆ 德国 Stiftung Warentest 2022 年的结果显示,消费者对 ModelDerm 的满意度仅略低于付费远程医疗咨询。
  • 童年时期经常出现颜色均匀的边框和清晰的斑点。总体来说,边框比这张图更清晰。
  • Cafe au lait macule 见于Neurofibromatosis type 1 (NF-1)
References Laser treatment for Cafe-au-lait Macules: a systematic review and meta-analysis 37291616 
NIH
激光治疗显示 75% 的 CALM 患者的清除率为 50%,其中 43% 的患者清除率为 75%。在不同的激光类型中,QS-1064-nm Nd:YAG 的效果最有效。总体而言,所有激光类型的副作用(例如色素沉着不足和色素沉着过度)均较低,表明安全性良好。
To draw a conclusion, the laser treatment could reach an overall clearance rate of 50% for 75% of the patients with CALMs, for 43.3% of the patients, the clearance rate could reach 75%. When looking at different wavelength subgroups, QS-1064-nm Nd:YAG laser exhibited the best treatment capability. Laser of all the wavelength subgroups presented acceptable safety regarding of the low occurrence of side effects, namely, hypopigmentation and hyperpigmentation.
 Cutaneous manifestations in neurofibromatosis type 1 32901776
Café-au-lait macules were shown in 1063 patients (96.5%), axillary and inguinal freckling in 991 (90%) and neurofibromas in 861 (78.1%). Other skin manifestations included: lipoma (6.2%), nevus anemicus (3.9%), psoriasis (3.4%), spilus nevus (3.2%), juvenile xanthogranuloma (3.2%), vitiligo (2.3%), Becker's nevus (1.9%), melanoma (0.7%) and poliosis (0.5%).
 Pigmentation Disorders: Diagnosis and Management 29431372
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules.